摘要 |
FIELD: phytopreparations. SUBSTANCE: universal method of preparing ergot alkaloids is based on extraction with acid aqueous acetone solution, extract evaporation, conversion of ergoalkaloid salts to free bases by change of medium pH to alkaline value followed by extraction of total ergoalkaloids with chloroform, evaporation of chloroform extract to dry residue, dissolving obtained total ergoalkaloids in ethyl acetate, crystallization and filtration of ready product. Purity degree of ergoalkaloids is 96-98% at retained yield. EFFECT: simplified technology, enhanced purity. |