| 发明名称 |
NEPRILYSIN INHIBITORS. |
| 摘要 |
In one aspect, the invention relates to compounds having the formula (I): where R1-R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising these compounds; methods of using these compounds; and processes and intermediates for preparing these compounds. |
| 申请公布号 |
MX2016009760(A) |
申请公布日期 |
2016.11.08 |
| 申请号 |
MX20160009760 |
申请日期 |
2015.01.29 |
| 申请人 |
THERAVANCE BIOPHARMA R&D IP, LLC |
发明人 |
Melissa FLEURY;Adam D. HUGHES;Anne- Marie BEAUSOLIEL;Daniel D. LONG;Donna A. A. WILTON |
| 分类号 |
C07D405/14;C07C229/34;C07C271/22;C07D231/14;C07D231/18;C07D231/20;C07D233/70;C07D233/90;C07D235/08;C07D237/14;C07D239/34;C07D249/10;C07D249/12;C07D249/18;C07D261/12;C07D263/18;C07D295/10;C07D309/40;C07D319/06;C07D401/04;C07D403/06;C07D405/12;C07D471/04 |
主分类号 |
C07D405/14 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
