发明名称 |
Immunotoxins specific for cd80 and cd86 expressing cells |
摘要 |
A method for treating autoimmune diseases comprising administering to a patient in need of such treatment a therapeutically effective amount of an immunotoxin comprising an anti-human CD86 monoclonal antibody IG10H6D10 as deposited in the ECACC collection under No. 95060210 or a humanized antibody, a single-chain antibody or fragments and specificity of said monoclonal antibody, coupled to a toxin or active fragments thereof wherein the binding of the immunotoxin to CD86 results in the killing of the CD86 expressing cell. |
申请公布号 |
AU6301696(A) |
申请公布日期 |
1996.12.30 |
申请号 |
AU19960063016 |
申请日期 |
1996.06.07 |
申请人 |
INNOGENETICS N.V. |
发明人 |
MARK DEBOER;G. C. DE GAST |
分类号 |
C12N15/02;A61K39/395;A61K47/48;A61P29/00;A61P35/00;A61P35/02;A61P37/00;A61P37/02;C12P21/08;C12R1/91 |
主分类号 |
C12N15/02 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|