发明名称 Neue Carbamoylderivate und deren Verwendung als 5-HT ¶1¶¶A¶-Antagonisten
摘要 The invention relates to novel piperidine and pyrrolidine derivatives of formula (I) in which R<1>, R<2>, R<3>, k, l, m and n have the meanings indicated in Claim 1, and their salts, novel intermediates and processes for the preparation of the compounds according to the invention. The compounds of formula (I) act as 5-HT1A receptor antagonists and exhibit 5-HT reuptake-inhibiting actions and can be used for the production of medicaments.
申请公布号 DE19615232(A1) 申请公布日期 1997.10.23
申请号 DE1996115232 申请日期 1996.04.18
申请人 MERCK PATENT GMBH, 64293 DARMSTADT, DE 发明人 ANDERSSON, BENGT RONNY, DIPL.-CHEM. DR., GOETEBORG, SE;HANSSON, LARS OLOV, DIPL.-CHEM. DR., GOETEBORG, SE;SONESSON, CLAS AKE, DIPL.-CHEM. DR., BILLDAL, SE;STJERNLOEF, NILS PETER, DIPL.-CHEM. DR., FROELIINDA, SE;MAERZ, JOACHIM, DIPL.-CHEM. DR., 55128 MAINZ, DE;BOETTCHER, HENNING, DIPL.-CHEM. DR., 64287 DARMSTADT, DE;DEVANT, RALF, DIPL.-CHEM. DR., 64291 DARMSTADT, DE;GREINER, HARTMUT, DIPL.-CHEM. DR., 64331 WEITERSTADT, DE;BARTOSZYK, GERD, DIPL.-PSYCH., 64331 WEITERSTADT, DE;HARTING, JUERGEN, DR., 64287 DARMSTADT, DE;SEYFRIED, CHRISTOPH, DIPL.-CHEM. DR., 64342 SEEHEIM-JUGENHEIM, DE
分类号 C07D211/14;A61K31/00;A61K31/40;A61K31/403;A61K31/404;A61K31/44;A61K31/4427;A61K31/443;A61K31/4439;A61K31/445;A61K31/4465;A61K31/4523;A61K31/454;A61K31/4545;A61K31/55;A61P25/04;A61P43/00;C07D207/06;C07D401/04;C07D401/06;C07D401/12;C07D401/14;C07D403/04;C07D405/04;C07D405/14;(IPC1-7):C07D401/14;A61K31/475 主分类号 C07D211/14
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