GABA a receptor subtypes and methods for screening drug compounds using imidazoquinoxalines and pyrrolopyrimidines to bind to GABAa receptor subtypes

摘要

PCT No. PCT/US93/03920 Sec. 371 Date Oct. 28, 1994 Sec. 102(e) Date Oct. 28, 1994 PCT Filed Apr. 30, 1993 PCT Pub. No. WO93/22681 PCT Pub. Date Nov. 11, 1993Disclosed are methods for screening compounds for potential therapeutic activity based on selective binding to GABAa receptors, and where the methods employ compounds of formulas I and II shown herein.