PYRIDAZINONE DERIVATIVES_AND THEIR USE AS INHIBITORS OF PROSTAGLANDIN G/H SYNTHASE I AND II(COX I AND II)

摘要

Compounds of formula I: <IMG> I where: R10 is a group represented by formula (A), (B), or (C): <IMG> , <IMG> , or <IMG> A B C and the other substituents are as defined in the specification; and their pharmaceutically acceptable salts are inhibitors of prostaglandin G/H synthase and are anti-inflammatory and analgesic agents.