发明名称 Certain fused pyrrolecarboxamides; a new class of gaba brain receptor ligands
摘要 The present invention encompasses structures of the formula: or the pharmaceutically acceptable non-toxic salts thereof wherein: wherein: W represents substituted or unsubstituted phenyl; X is hydrogen, T is hydrogen, and n is 3, which compounds are highly selective agonists, antagonists or inverse agonists for GABAa brain receptors or prodrugs of agonists, antagonists or inverse agonists for GABAa brain receptors. These compounds are useful in the diagnosis and treatment of anxiety, sleep and seizure disorders, overdose with benzodiazepine drugs and for enhancement of memory.
申请公布号 AU2832897(A) 申请公布日期 1998.02.09
申请号 AU19970028328 申请日期 1997.05.09
申请人 NEUROGEN CORPORATION 发明人 PAMELA ALBAUGH;GANG LIU;ALAN HUTCHISON
分类号 A61K31/404;C07C233/58;C07D209/08;C07D209/42;C07D209/52;C07D307/84;C07D401/12;C07D403/12;C07D405/12;C07D409/12;C07D413/04;C07D417/12;C07D471/04 主分类号 A61K31/404
代理机构 代理人
主权项
地址