A PHARMACEUTICAL COMPOSITION CONTAINING COMBINATIONS OF NICOTINAMIDE AND 5-AMINOSALICYLIC ACID FOR BENEFICIALLY INFLUENCING THE INTESTINAL MICROBIOTA AND/OR TREATING GASTROINTESTINAL INFLAMMATION

摘要

The present invention relates to a new pharmaceutical composition containing a combination of 5-aminosalicylic acid and nicotinamide or related compounds. The combination is believed to beneficially influence the intestinal microbiota and/or reduce gastrointestinal inflammation. In certain embodiments, the pharmaceutical composition is partially or entirely released into the small intestine or large intestine.

主权项

1. A pharmaceutical composition comprising a combination of 5-aminosalicylic acid or a prodrug thereof and one or more active substances selected from nicotinamide; a compound that converts in the body of an animal or human into nicotinamide; nicotinamide adenine dinucleotide (NAD); nicotinamide adenine dinucleotide phosphate (NADP); an intermediate in the biosynthesis of NAD or NADP.