IMPROVEMENTS IN AND RELATING TO FORENSIC IDENTIFICATION

摘要

The invention provides improved allelic ladder mixtures, and individual alleles suitable for use in such mixtures, the allelic ladder mixture comprising one or more of the following allelic ladders : i) an allelic ladder fro locus HUMVWFA31/A comprising one or more of alleles comprising or consisting of sequences : TCTA TCTG TCTA (TCTG)4 (TCTA)~; TCTA (TCTG), (TCTA)~; OR (TCTA)~ (TCTG)4 (TCTA) ~ TCCA (TCTA)~ or at least 75% homologous thereto: ii) an allelic ladder for locus HUMTHO1 comprising or consisting of sequence: (TCAT)~ CAT (TCAT)~ TCGT TCAT; or at least 75% homologous thereto; iii) an allelic ladder for locus D8S1179 comprising one or more of alleles (TCTA)~; (TCTA)2 TCTC (TCTA)~ or at least 75% homologous thereto; iv) an allelic ladder for locus HUMFIBRA/FGA comprising one or more of alleles comprising or consisting of the sequences:- (see fig. I) ; or ; or at least 75% homologous thereto; v) an allelic ladder for locus D21S11 comprising one or more of alleles comprising or consisting of sequences , or ; or at least 75% homologous thereto; iv) an allelic ladder for locus D18S51 comprising an allele comprising or consisting of sequence : (AGAA)~; or at least 75% homologous thereto. The allelic ladder mixtures give improved identification and distinguishing capabilities, particularly suitable in forensic investigations.