发明名称 Piperazine based cytofectins
摘要 The present invention relates to piperazine based amphilic cationic lipids useful for gene therapy, transfection, and introducing immunogenic compounds for the purpose of vaccination. The disclosed compounds have lipophilic moieties linked to the ring nitrogens. In addition, at least one of the ring nitrogens is quatranized and linked to a hydrocarbon having at least one heteroatom.
申请公布号 US5861397(A) 申请公布日期 1999.01.19
申请号 US19960726348 申请日期 1996.10.03
申请人 VICAL INCORPORATED 发明人 WHEELER, CARL J.
分类号 C07D295/08;A61K47/48;A61K48/00;C07D295/088;C07D295/12;C07D295/13;C07D295/18;C07D295/215;(IPC1-7):A01N43/58;A01N25/26;A61K31/50;A61K39/00 主分类号 C07D295/08
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