| 发明名称 |
DERIVATIVE OF INTERCELLULAR ADHESION ICAM-1 SUBSTANCE, DNA SEQUENCE |
| 摘要 |
FIELD: molecular biology, biotechnology, medicine. SUBSTANCE: invention proposes a derivative that has five successively located immunoglobulin ICAM-1 domains and a cytoplasmatic domain ICAM-1 or transmembrane domain ICAM-1. DNA encoding a derivative of ICAM-1 is obtained by recombinant procedure. Derivative of ICAM-1 can be used as a highly effective antiinflammatory agent. EFFECT: enhanced effectiveness of a derivative. 3 dwg, 1 tbl, 1 ex
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| 申请公布号 |
RU2126449(C1) |
申请公布日期 |
1999.02.20 |
| 申请号 |
RU19920016375 |
申请日期 |
1989.09.28 |
| 申请人 |
DANA FARBER KENZER INSTITJUT |
发明人 |
TIMOTI EHLEN SPRINGER;ROBERT ROTLEJN;STIVEN DIN MERLIN;MAJKEL LORAN DASTIN |
| 分类号 |
C12N15/12;A01K39/00;A61K;C07K;C07K14/705;C12N;C12N5/12;C12P21/08;G01N;(IPC1-7):C12N15/12 |
主分类号 |
C12N15/12 |
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