发明名称 AGENT FOR TREATMENT OF CERVICAL VERTEBRAL SPRAIN
摘要 PROBLEM TO BE SOLVED: To obtain a treating agent useful for the mitigation of pain of cervical vertebral sprain and preventing the prolonged duration of the pain by making the treating agent include an aminoalkoxybibenzyl compound as an active component. SOLUTION: A compound of formula I R1 is H, a halogen or the like; R2 is H, a 1-5C alkoxy or the like; R3 is H, hydroxyl or the like; R4 is a group of formula N(R5)(R6) (R5 and R6 are each H or a 1-8C alkyl) or formula II [A is a (substituted) 3-5C alkylene]; (m) is 0-5}, e.g. (±)-1- o-[2-(m- methoxyphenyl)ethyl]phenoxy}-3-(dimethylamino)-2-propyl hydrogen succinate hydrochloride of formula III (the general name is salpogrelate hydrochloride) is used as an active component. The daily administration rate of the agent for adult is preferably 0.5-50 mg/kg in terms of the active component by oral administration.
申请公布号 JP2000034228(A) 申请公布日期 2000.02.02
申请号 JP19980203027 申请日期 1998.07.17
申请人 MITSUBISHI CHEMICALS CORP 发明人 YOSHIDA MITSUGI
分类号 C07D295/08;A61K31/135;A61K31/195;A61K31/215;A61K31/395;A61K31/445;A61P43/00;(IPC1-7):A61K31/215 主分类号 C07D295/08
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