| 发明名称 |
ASYMMETRIC SYNTHESIS OF BENZOXAZINONES |
| 摘要 |
<p>The present invention provides novel methods for the asymmetric synthesis of (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1 -benzoxazin-2-one of formula (VI-i) which is useful as a human immunodeficiency virus (HIV) reverse transcriptase inhibitor.</p> |
| 申请公布号 |
SI20071(A) |
申请公布日期 |
2000.04.30 |
| 申请号 |
SI19970020079 |
申请日期 |
1997.12.15 |
| 申请人 |
DUPONT PHARMACEUTICALS COMPANY |
发明人 |
PIERCE MICHAEL ERNEST;CHOUDHURY ANUSUVA;RARSONS RODNEY LAWRENCE |
| 分类号 |
A61K31/535;A61P31/18;A61P43/00;C07D265/18;(IPC1-7):C07D265/18 |
主分类号 |
A61K31/535 |
| 代理机构 |
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