发明名称 |
Method for obtaining recombinant hbsag |
摘要 |
The present invention relates to a method for recovering recombinant HBsAg, wherein recombinant methylotrophic yeast cells which are capable of expressing HBsAg are disrupted using a high pressure homogenizer, and HBsAg is recovered from the cell debris obtained. The inventive method is characterized by a high product yield per g of cell dry weight and thus constitutes a considerable improvement over the former methods for recovering HBsAg. |
申请公布号 |
AU4748500(A) |
申请公布日期 |
2000.11.10 |
申请号 |
AU20000047485 |
申请日期 |
2000.04.17 |
申请人 |
RHEIN BIOTECH GESELLSCHAFT FUR NEUE BIOTECHNOLOGISCHE PROZESSE |
发明人 |
MICHAEL PIONTEK;MICHAEL WENIGER |
分类号 |
C07K14/02;C12N1/06;C12N1/19;C12N15/31;C12N15/36 |
主分类号 |
C07K14/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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