Tissue Plasminogen Activators (Improved Variants)

摘要

1. Technical Result Increase in efficiency of vascular state or treatment of vascular diseases in mammals, widening of the assortment anticoagulants. 2. Essence By means of gene engineering there are obtained novel variants of tissue plasminogen activators of human, which are characterized with extended circulatory half-life and improved fibrinolytic potency. There are created pharmaceutical compositions against fibrin accumulation, adhesion and reformation. 3. Field of Application Medicine, therapy. Figures: 6