发明名称 |
Highly productive packaging lines |
摘要 |
The invention concerns a packaging eukaryotic cell for the production of defective infections viruses carrying a transgene, characterized in that it is deficient in one cell function essential to its growth, in particular in the presence of a selection culture medium, the said function being capable of being restored by the expression of an exogenous sequence introduced in the cell: either with a vector carrying transcomplementing functions of packaging cells; or with a vector carrying a transgene, and enabling the selection in a selective medium of cells carrying the said exogenous sequence.
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申请公布号 |
US2002123146(A1) |
申请公布日期 |
2002.09.05 |
申请号 |
US20010978931 |
申请日期 |
2001.10.15 |
申请人 |
UNIVERSITE PIERRE ET MARIE CURIE |
发明人 |
KLATZMANN DAVID;SALZMANN JEAN-LOUP |
分类号 |
C12N15/09;A61K48/00;A61P35/00;A61P37/00;C12N5/10;C12N15/867;(IPC1-7):C12N15/867;C12N7/01;C12N5/08 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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