发明名称 FORMULATION OF SUBSTITUTED BENZIMIDAZOLES.
摘要 <p>The present invention relates to stable liquid formulations that comprise a water free or almost water free, polyethylene glycol solution of sodium or potassium salt of a Hplus;, Kplus; ATPase inhibitor of formula (I) or a sodium or potassium salt of one single enantiomer thereof. Alternatively, the sodium or potassium salt of the Hplus;, Kplus; ATPase inhibitor may be formed in situ in the polyethylene glycol solution by adding sodium or potassium hydroxide together and the active compound. The invention is also directed to the preparation of the claimed formulation, use of the stable liquid formulations in medicine and in the treatment of gastrointestinal diseases.</p>
申请公布号 MXPA02003900(A) 申请公布日期 2002.09.30
申请号 MX2002PA03900 申请日期 2000.10.13
申请人 ASTRAZENECA AB. 发明人 MIKAEL BR°LLS.
分类号 A61K47/34;A61K9/00;A61K9/08;A61K31/4164;A61K31/4184;A61K31/422;A61K31/44;A61K31/4439;A61K47/10;A61K47/30;A61K47/32;A61P1/04 主分类号 A61K47/34
代理机构 代理人
主权项
地址
您可能感兴趣的专利