| 发明名称 |
HYDROXAMATE-BASED INHIBITORS OF DEACETYLASES B |
| 摘要 |
The present teachings relate to compounds of Formula (I) and pharmaceutically acceptable salts, hydrates, esters, and prodrugs thereof, (see formula I); wherein R1, R2, R3, Y, Z, and (A) are as defined herein. The compounds are useful for the inhibition of HDAC-1 and HCT116. |
| 申请公布号 |
CA2719477(C) |
申请公布日期 |
2016.11.08 |
| 申请号 |
CA20092719477 |
申请日期 |
2009.03.24 |
| 申请人 |
NOVARTIS AG |
发明人 |
SHULTZ, MICHAEL;CHEN, CHRISTINE, HIU-TUNG;CHO, YOUNG SHIN;JIANG, LEI;FAN, JIANMEI;LIU, GANG;MAJUMDAR, DYUTI;LI, JIANKE |
| 分类号 |
C07D207/08;A61K31/4025;A61P35/00;C07D401/06;C07D403/06;C07D405/06;C07D413/06;C07D471/04 |
主分类号 |
C07D207/08 |
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