发明名称 Catechols as antimicrobial agents
摘要 Compounds, pharmaceutically acceptable salts, and compositions thereof of the general formula:wherein Ar is aryl and heteroaryl; R1, R2, R3, and R4 are hydrido, alkyl, cyano, heteroaryl, hydroxy, amino, acylamino, halo, alkoxy, aryloxy, carboxyamido, alkenyl, cycloalkyl, heterocyclyl, acyl, acyloxy, carboalkoxy, carboxy, thio, sulfinyl, sulfonyl and sulfoxy, R5, R6, R7, and R8 are hydrido and lower alkyl; and Het is a nitrogen-containing heterocyclic ring.
申请公布号 US6545015(B2) 申请公布日期 2003.04.08
申请号 US20010934743 申请日期 2001.08.22
申请人 MERCK & CO., INC. 发明人 HAMMOND MILTON L.;LEEMAN AARON H.;MALETIC MILANA;SANTORELLI GINA M.;WADDELL SHERMAN T.;FINN JOHN;MORYTKO MICHAEL;HILL JASON;KEITH DENNIS
分类号 A61K31/4184;A61K31/437;A61K31/454;A61P31/04;A61P31/10;C07D215/14;C07D233/54;C07D235/12;C07D401/12;C07D403/12;C07D405/12;C07D471/04;C07D521/00;(IPC1-7):C07D215/00 主分类号 A61K31/4184
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