发明名称 Condensed-hexacyclic compounds and a process therefor
摘要 Disclosed are a process for the preparation of a compound represented by the formula (1), which comprises treating a compound represented by the formula (2) with methanesulfonic acid and then subjecting the thus-treated compound to recrystallization; and Compound (1) so obtained.This Compound (1) is free of hygroscopicity, excellent in filterability and solubility and easy in handling. Furthermore, according to the preparation process of the present invention, an unnecessary isomer can be converted into the target one and separation of the target isomer can be conducted easily.
申请公布号 US6552197(B2) 申请公布日期 2003.04.22
申请号 US20010876945 申请日期 2001.06.11
申请人 DAIICHI PHARMACEUTICAL CO., LTD.;KABUSHIKI KAISHA YAKULT HONSHA 发明人 KAMIHARA SHINJI;KANAI KAZUAKI;NOGUCHI SHIGERU;TERASAWA HIROFUMI;KITAOKA HIROAKI
分类号 C07D491/22;(IPC1-7):C07D471/00 主分类号 C07D491/22
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