发明名称 |
Antimicrobial polymeric surfaces |
摘要 |
Bactericidal compositions are disclosed that comprise a polymeric compound immobilized on a material. Medical devices are also disclosed which comprise such a bactericidal composition. Methods are disclosed for covalently derivatizing the surfaces of common materials with an antibacterial polycation, e.g., poly(vinyl-N-pyridinium bromide); the first step of the methods involves coating the surface with a nanolayer of silica. Various commercial synthetic polymers derivatized in this manner are bactericidal, i.e., they kill on contact up to 99% of deposited Gram-positive and Gram-negative bacteria, whether deposited through air or water.
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申请公布号 |
US2003091641(A1) |
申请公布日期 |
2003.05.15 |
申请号 |
US20020123860 |
申请日期 |
2002.04.16 |
申请人 |
TILLER JOERG C.;LIAO CHUN-JEN;LEWIS KIM;KLIBANOV ALEXANDER M. |
发明人 |
TILLER JOERG C.;LIAO CHUN-JEN;LEWIS KIM;KLIBANOV ALEXANDER M. |
分类号 |
A01N43/40;A61L27/34;A61L27/50;(IPC1-7):A61K31/785;A61K9/14 |
主分类号 |
A01N43/40 |
代理机构 |
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