发明名称 THERAPEUTIC QUINOLONE COMPOUNDS WITH 5-HT-ANTAGONISTIC PROPERTIES.
摘要 <p>Provided herein is a compound having the formula (I) (R2 is typically a tertiary nitrogen atom, being either alkyl-substituted or member of q heterocyclic ring; R7 is typically a monocyclic or bicyclic aromatic ring or a heterocyclic ring) wherein said compounds are useful for the treatment of psychiatric disorders including but not limited to depression, generalized anxiety, eating disorders, dementia, panic disorder, and sleep disorders. The compounds may also be useful in the treatment of gastrointestinal disorders, cardiovascular regulation, motor disorders, endocrine disorders, vasospasm and sexual dysfunction. The compounds are 5HT1B and 5HT1D antagonists.</p>
申请公布号 MXPA04004074(A) 申请公布日期 2004.07.23
申请号 MX2004PA04074 申请日期 2002.11.01
申请人 ASTRAZENECA AB 发明人 JOHN MACCAULEY
分类号 C07D215/42;A61K31/496;A61K31/5377;A61K31/541;A61K31/551;A61P1/00;A61P1/14;A61P3/04;A61P5/00;A61P9/00;A61P15/00;A61P15/10;A61P21/00;A61P21/02;A61P25/14;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P43/00;C07D207/14;C07D215/233;C07D215/48;C07D241/04;C07D243/08;C07D265/30;C07D311/24;C07D311/66;C07D401/04;C07D401/12;C07D401/14;C07D405/04;C07D405/12;C07D405/14;C07D413/06;C07D413/12;C07D413/14;C07D417/04;C07D417/12;C07D521/00;(IPC1-7):A61K31/402;A61K31/537 主分类号 C07D215/42
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