BIOMARKERS FOR MULTIPLE MYELOMA

摘要

The present disclosure is directed to a molecular signature useful in the identification multiple myeloma cells. The molecular signature advantageously identifies multiple myeloma cells under both normoxic and hypoxic conditions. The disclosed molecular signature may be used to diagnose, prognose and monitor multiple myeloma.

主权项

1. A method for detecting multiple myeloma (MM) cells in a biological sample, the method comprising:
a) analyzing the biological sample for the presence of CD38 positive, CD3 negative, CD19 negative, CD14 negative, CD16 negative and CD123 negative cells; and b) identifying the biological sample as having MM cells if CD38 positive, CD3 negative, CD19 negative, CD14 negative, CD16 negative and CD123 negative cells are present in the biological sample.