| 发明名称 |
isoquinolinas e isoquinolinonas substituídas como inibidores da rho-quinase |
| 摘要 |
The invention relates to substituted isoquinoline and isoquinolinones of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds. |
| 申请公布号 |
BRPI0914696(A2) |
申请公布日期 |
2016.10.18 |
| 申请号 |
BR2009PI14696 |
申请日期 |
2009.06.19 |
| 申请人 |
SANOFI-AVENTIS |
发明人 |
FRÉDÉRIC JEANNOT;HEINZ-WERNER KLEEMANN;JOHN WESTON;KATRIN LORENZ;MATTHIAS LOEHN;OLIVER PLETTENBURG;OLIVIER DUCLOS |
| 分类号 |
C07D217/24;A61K31/472;A61P9/00;A61P25/00;A61P27/00;A61P37/00 |
主分类号 |
C07D217/24 |
| 代理机构 |
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代理人 |
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