发明名称 |
METHOD FOR INCREASING THE BIOAVAILABILITY OF INHALED COMPOUNDS |
摘要 |
The present invention relates to a compound comprising one or more PEG moieties, wherein said compound is a therapeutic agent active for treating a respiratory disease. The present invention also relates to the use of a PEGylated therapeutic agent for treating a respiratory disease. Another object of the invention is a method for enhancing the bioavailability of a therapeutic agent, for enhancing the pulmonary residency of a therapeutic agent and/or for reducing the pulmonary clearance of a therapeutic agent, wherein said methods comprise the PEGylation of the therapeutic agent. |
申请公布号 |
US2016331839(A1) |
申请公布日期 |
2016.11.17 |
申请号 |
US201515111564 |
申请日期 |
2015.01.16 |
申请人 |
UNIVERSITE CATHOLIQUE DE LOUVAIN ;UNIVERSITE DE LIEGE |
发明人 |
VANBEVER Rita;KOUSSOROPLIS Salome;CATALDO Didier;VAN SNICK Jacques |
分类号 |
A61K47/48;C07K16/24;A61K9/00;A61K38/57;A61K38/46;A61K38/17 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Louvain-la-Neuve BE |