Fremgangsmate for fremstilling av baccatin i naervaere av et enzym og en acetyldonor, enzymet, fremgangsmate for fremstilling av dette og fremgangsmate for fremstilling av taxol og/eller taxolderivater.

摘要

A process for preparing baccatin and/or baccatin derivatives is described in which 10-deacetylbaccatin or a 10-deacetylbaccatin derivative is reacted in the presence of an isolated enzyme and an acetyl donor, the enzyme used being an acetyl transferase having a molecular weight of from 70 to 72 kD, determined by SDS-PAGE, which acetyl transferase is obtainable from Taxus chinensis cell cultures.