| 摘要 |
PROBLEM TO BE SOLVED: To obtain a composition for smoking cessation through eliminating craving for nicotine. SOLUTION: An improved nicotine lozenge is utilized to satisfy transient craving for nicotine. The lozenge contains nicotine, a nonnutritive sweetener and an absorbent excipient. The nonnutritive sweetener comprises a substance selected from polyol sweetener, saccharin, cyclamate and aspartame and a substance selected from ammonium glycyrrhizinate, neohesperidin-dihydrochalcone and stevioside, while the absorbent excipient is mannitol orβ-cyclodextrin. COPYRIGHT: (C)2006,JPO&NCIPI |
