FREMGANGSMÅDE TIL SYNTESE AF 4-(3-METHANSULFONYLPHENYL)-1-N-PROPYL-PIPERIDIN.
摘要
The present invention is directed to processes for the preparation of 4-(3-methanesulfonyl-phenyl)-1-N-propylpiperidine (I) or a pharmaceutically acceptable salt thereof, which comprises: oxidizing a sulfide of the formula (II): with a catalytic oxidizing agent and an oxidant; to give a compound of the formula (III): followed by catalytic reduction of the compound of formula (III).
申请公布号
DK1802573(T3)
申请公布日期
2016.12.19
申请号
DK20050793645T
申请日期
2005.10.13
申请人
Teva Pharmaceuticals International GmbH
发明人
GAUTHIER, Donald, R.;DESMOND, Richard;DEVINE, Paul, N.