发明名称 |
Cycloalkylmethylaminobenzophenon-derivater til anvendelse som mellemprodukter ved fremstillingen af 1-cycloalkylmethyl-5-pheny-1H-1,4-benzodiazepin-2(3H)-oner. |
摘要 |
<p>The invention comprises (a) 2-cycloalkylmethylamino-5-halobenzophenones, which are prepared by oxidizing a 2-cycloalkylmethylamino-5-halobenzhydrol with an excess of manganese dioxide, (b) 2-cycloalkylmethylamino-5-halobenzhydrols, which are prepared by reducing a 2-cycloalkylcarbonylamino - 5 - halobenzophenone with an excess of an alkali metal complex hydride followed by aqueous hydrolysis, and (c) 2 - cycloalkylcarbonylamino - 5 - halobenzophenones, which are prepared by treating a 2-amino-5-halobenzophenone dissolved in a mixture of tetrahydrofuran and triethylamine with an equimolar proportion of a cycloalkanecarboxylic acid chloride, followed by refluxing the reaction mixture.</p> |
申请公布号 |
DK128891(B) |
申请公布日期 |
1974.07.22 |
申请号 |
DK19650000765 |
申请日期 |
1965.02.12 |
申请人 |
WARNER-LAMBERT PHARMACEUTICAL COMPANY |
发明人 |
FREEMAN HAGER MCMILLAN;IAN PATTISON |
分类号 |
C07C233/00;C07D209/48;C07D243/24;C07D243/32;(IPC1-7):C07C97/10 |
主分类号 |
C07C233/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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