INFLUENCE OF GENOTYPE ON SUSCEPTIBILITY TO TREATMENT WITH FISH OIL

摘要

The present invention relates to methods for assessing an individual's susceptibility to treatment of an inflammatory disease with a dietary supplement. The invention describes the recognition that the sensitivity of an individual to the inflammation suppressing effects of fish oil on TNF-α production is linked both to genetic variation encoded by, or associated with, TNF-α, LT-α and/or IL-6 single nucleotide polymorphisms and to the inherent level of production of TNF-α by cells.