发明名称 |
WT1-ANTIGEN PEPTIDE CONJUGATE VACCINE |
摘要 |
The present invention provides a compound represented by the formula (1):
wherein X a and Y a are each a single bond and the like,
cancer antigen peptide A is an MHC class I-restricted WT1 peptide consisting of 7 - 30 amino acid residues, R 1 is a hydrogen atom, a group represented by the formula (2):
wherein X b and Y b are each a single bond and the like,
cancer antigen peptide B has a sequence different from that of the cancer antigen peptide A, and is an MHC class I-restricted WT1 peptide consisting of 7 - 30 amino acid residues, or cancer antigen peptide C, and
cancer antigen peptide C has a sequence different from that of the cancer antigen peptide A, and is an MHC class I-restricted WT1 peptide or an MHC class II-restricted WT1 peptide, consisting of 7 - 30 amino acid residues containing one cysteine residue,
or a salt thereof, and the like. |
申请公布号 |
EP2982681(A4) |
申请公布日期 |
2016.10.19 |
申请号 |
EP20140775899 |
申请日期 |
2014.03.28 |
申请人 |
SUMITOMO DAINIPPON PHARMA CO., LTD.;INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC. |
发明人 |
LI, CHIANG JIA;BAN, HITOSHI;NISHIO, YUKIHIRO;GOTO, MASASHI;NISHIHARA, TOSHIO;TAKANASHI, YOSUKE |
分类号 |
C07K7/06;A61K39/00;A61P35/00;C07K7/08;C07K14/00 |
主分类号 |
C07K7/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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