主权项 |
1. A method for making a compound of Formula (I) comprising:
combining [1.1.1 ]propellane; a Group VII transition metal compound or a Group IX transition metal compound; a hydride source; and a reagent capable of contributing all or a part of a substituent group such that bicyclo[1.1.1]pentane is substituted with the substituent group; wherein the compound of Formula (I) has the structure: wherein: R1 is N3, F, Cl, Br, I, CN, OH, SCN, NCO, NO, —C(═NOR2)(CN) or —CH(⊚NOR2); and R2 is (C1 to C10) alkoxy, substituted or unsubstituted (C1 to C30) alkyl, substituted or unsubstituted aryl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkenyl, substituted or unsubstituted cycloalkynyl, substituted or unsubstituted heterocycle, substituted or unsubstituted heteroaryl, substituted or unsubstituted aryl(alkyl), substituted or unsubstituted alkyl(aryl), or substituted or unsubstituted heteroaryl(alkyl). |