CRYSTALLINE CYTIDINE-51-DIPHOSPHATE CHOLINE MONOHYDRATE AND PRODUCTION THEREOF

摘要

Crystalline cytidine-5'-diphosphate choline monohydrate is produced by A. ADDING A HYDROPHILIC ORGANIC SOLVENT TO AN AQUEOUS SOLUTION SYSTEM OF CYTIDINE-5'-DIPHOSPHATE CHOLINE IN THE PH range of from about 2 to about 4, or B. KEEPING CYTIDINE-5'-DIPHOSPHATE CHOLINE STANDING AT A RELATIVE HUMIDITY OF NOT LESS THAN ABOUT 32 PERCENT AND AT A TEMPERATURE IN THE RANGE OF FROM ABOUT 17 DEG C to about 70 DEG C for not shorter than about 5 days.