发明名称 |
4A-AURYL-TRANS-DECAHYDROISOQUINOLINES |
摘要 |
<p>1436377 Isoquinoline derivatives E I DU PONT DE NEMOURS & CO 19 July 1973 [20 July 1972 1 June 1973] 39387/75 Divided out of 1436376 Heading C2C The invention comprises compounds of the formulµ where R<SP>1</SP> is H, C 1 -C 6 alkyl, benzyl, phenethyl or cycloalkylmethyl of the formula -CH 2 CH(CH 2 ) n where n is 2-5, R<SP>5</SP> is or Ar<SP>1</SP> is a group of the formula where R<SP>7</SP> is H or methoxy, R<SP>8</SP> is methoxy or two of R<SP>7</SP> or of R<SP>8</SP> on adjacent carbons may together form a methylenedioxy group with the proviso that R<SP>1</SP> is not H in compounds of Formulµ II or III. Compounds of Formula I where R<SP>1</SP> is H are prepared by treating a compound of the formula with R<SP>6</SP>OH and HCl where R<SP>6</SP> is C 1 -C 4 alkyl. The compounds may be alkylated and subsequently reduced to give compounds of Formula II or epoxidized to give compounds of Formula III.</p> |
申请公布号 |
CA1024149(A) |
申请公布日期 |
1978.01.10 |
申请号 |
CA19730176763 |
申请日期 |
1973.07.18 |
申请人 |
E.I. DU PONT DE NEMOURS AND COMPANY |
发明人 |
BRITTELLI, DAVID R.;RIPKA, WILLIAM C. |
分类号 |
C07D217/02;C07D217/04;C07D217/16;C07D217/24;C07D317/62 |
主分类号 |
C07D217/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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