Disclosed herein are methods of detecting Plasmodium in a subject (for example, presence of Plasmodium parasite) by detecting the presence and/or amount of one or more metabolites in a sample from the subject. In some embodiments, the methods include detecting in the sample one or more metabolites listed in Table 1, Table 2, and/or Tables 5-8. The amount of the one or more metabolites in the sample is compared to the amount of the one or more metabolites in a control and presence of Plasmodium is determined if the amount of the one or more metabolites is different (for example statistically significantly increased or decreased) compared to the control.
申请公布号
WO2016149386(A1)
申请公布日期
2016.09.22
申请号
WO2016US22666
申请日期
2016.03.16
申请人
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES;EMORY UNIVERSITY
发明人
SHI, Ya, Ping;SLUTSKER, Laurence;PARK, Youngja;JONES, Dean P.;LILI-WILLIAMS, Loukia