摘要 |
<p>of disclosure A process for the aerobic culture of a microorganism in a fluid nutrient medium therefor containing at least one source of carbon assimilable by the microorganism, in which a culture broth consisting of the fluid nutrient medium and of a cellular mass of the microorganism is circulated in a closed loop between an upper level and a lower level, in which the broth is subjected, in a fermentation zone extending along an ascending side of the loop from the lower level, to the combined action of the frictional forces of bubbles of an oxygen containing gas or of oxygen released under pressure into the broth, a mechanical force applying an upward thrust and at least one couple of mechanical forces acting in a horizontal plane.</p> |