| 主权项 |
1. A compound of Formula (I):or pharmaceutically acceptable salt thereof,
wherein
A is N or —CR4;X is —S—;R1, R4, R5, R6, R7, and R8 are independently hydrogen, halogen, —NH2, —OH, —NO2, —C(O)CH3, —NHC(O)CF3, —OC(O)CH3, or unsubstituted C1-4 alkyl;R2 and R3 are independently hydrogen, halogen, —N3, —CF3, —CCl3, —CBr3, —CI3, —CN, —CHO, —OH, —NH2, —COOH, —CONH2, —NO2, —SH, —SO2, —SO2Cl, —SO3H, —SO4H, —SO2NH2, —NHNH2, —ONH2, —NHC(O)NHNH2, R2a-substituted or unsubstituted C1-C8 alkyl, R2a-substituted or unsubstituted 2-8 membered heteroalkyl, R2a-substituted or unsubstituted C3-C8 cycloalkyl, R2a-substituted or unsubstituted 3-6 membered heterocycloalkyl, R2a-substituted or unsubstituted phenyl, or R2a-substituted or unsubstituted 5or 6 membered heteroaryl;R2a is independently hydrogen, halogen, —N3, —CF3, —CCl3, —CBr3, —CI3, —CN, —CHO, —OH, —NH2, —COOH, —CONH2, —NO2, —SH, —SO2, —SO2Cl, —SO3H, —SO4H, —SO2NH2, —NHNH2, —ONH2, —NHC(O)NHNH2, R2b-substituted or unsubstituted C1-C8 alkyl, R2b-substituted or unsubstituted 2-8 membered heteroalkyl, R2b-substituted or unsubstituted C3-C8 cycloalkyl, R2b-substituted or unsubstituted 3-6 membered heterocycloalkyl, R2b-substituted or unsubstituted phenyl, or R2b-substituted or unsubstituted 5or 6 membered heteroaryl; andR2b is independently hydrogen, halogen, —N3, —CF3, —CCl3, —CBr3, —CI3, —CN, —CHO, —OH, —NH2, —COOH, —CONH2, —NO2, —SH, —SO2, —SO2Cl, —SO3H, —SO4H, —SO2NH2, —NHNH2, —ONH2, —NHC(O)NHNH2, an unsubstituted C1-C8 alkyl, an unsubstituted 2-8 membered heteroalkyl, an unsubstituted C3-C8 cycloalkyl, an unsubstituted 3-6 membered heterocycloalkyl, an unsubstituted phenyl, or an unsubstituted 5or 6 membered heteroaryl;wherein if A is —CR4 then at least one of R1, R2, R3, R4, R5, R6, R7, and R8 is not hydrogen or alkyl. |
