COMPOUNDS WITH ERGOLINE SKELETON AND A PROCESS FOR THE PREPARATION THEREOF

摘要

New compounds of the general formula (I) (I) wherein R stands for hydrogen or methyl or methyl group, x y stands for a group of the formula or , and R1 stands for a group of the formula (III), (IV) or (V) (III) (IV) (V) wherein n is an integer from 4 to 10, are prepared by acylating a compound of the general formula(II), (II) wherein R and each have the same meanings as defined above, and R2 stands for a group of the formula (VI), (VII) or (VIII), (VI) (VII) (VIII) with a C6-12 carboxylic acid or a C6-12 carboxylic acid halide, The new compounds of the general formula (I) and their acid addition salts can be used as antidepressants and antiserotonine agents with prolonged effects.