| 摘要 |
<p>This invention relates to a novel organic nitrate tablet composition, comprising polyvinylpyrrolidone and an organic nitrate therapeutic agent, and to compressed tablets thereof, and more particularly to a new and improved form of compressed tablet for sublingual administration to the prophylaxis and treatment of acute coronary attacks, which is capable of rapid disintegration when administered thereby allowing rapid buccal absorption of the therapeutic agent contained in said tablet. The present invention also relates to a method of producing sublingual tablets, containing polyvinylpyrrolidone and an organic nitrate therapeutic agent, with an improved formulation which gives an extended shelf life and stabilized potency to the tablets.</p> |
