| 发明名称 |
PHARMACEUTICALLY ACCEPTABLE COCRYSTALS OF N-[2-(7-METHOXY-1-NAPHTYL)ETHYL]ACETAMIDE AND METHODS OF THEIR PREPARATION |
| 摘要 |
The present invention relates to novel solid forms of agomelatine (I), specifically novel pharmaceutically acceptable cocrystals thereof, as well as to methods of preparing them. Two pharmaceutically acceptable cocrystals of (I) that have physicochemical properties acceptable for pharmaceutical development were obtained. |
| 申请公布号 |
EA024422(B1) |
申请公布日期 |
2016.09.30 |
| 申请号 |
EA20130091574 |
申请日期 |
2012.04.25 |
| 申请人 |
ZENTIVA, K.S. |
发明人 |
MILLER GARY, JAMES;RIDVAN LUDEK;RICHTER JINDRICH;DAMMER ONDREJ;CHVOJKA TOMAS;PEKAREK TOMAS;HEYSE WINFRIED;NAGEL NORBERT |
| 分类号 |
A61K31/165;A61K31/185;A61K31/194;A61P25/24;C07C57/145;C07C59/265;C07C233/18;C07C309/29 |
主分类号 |
A61K31/165 |
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