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1. A system for measurement of at least two hemoglobin species in a patient's blood sample by spectroscopy, and measurement of at least pH of the blood sample by biosensor, for assessing the patient's oxygenation and acid-base status, the system comprising:
a disposable cartridge for processing a portion of the blood sample, the cartridge comprising a housing having:
a cartridge inlet for engaging one of a syringe containing the blood sample and a capillary adaptor for transferring a portion of the blood sample from a puncture site of a body part of the patient to the cartridge;a blood storage conduit having a proximal end close to the cartridge inlet and a distal end away from the cartridge inlet;a blood storage conduit entrance at the proximal end of the blood storage conduit;an optical chamber for receiving the blood from the distal end of the blood storage conduit and for measuring the at least two hemoglobin species;an optical chamber overflow chamber fluidly connected with the optical chamber;at least one optical window, wherein at least a portion of the at least one optical window is in alignment with at least a portion of the optical chamber;a biosensor conduit for receiving the blood from the optical chamber overflow chamber, the biosensor conduit comprising at least a portion of a pH biosensor;an air bladder;an air bladder exit port, having an arrangement with the blood storage conduit entrance for providing pressurized air to the blood storage conduit via the blood storage conduit entrance, for urging the blood into the biosensor conduit;a waste receptacle for receiving liquid waste from the biosensor conduit; anda waste receptacle vent for relieving pressure in the waste receptacle; a cap for sealing the cartridge inlet; and, an analyzer comprising:
an analyzer housing;a slot in the analyzer housing for receiving the disposable cartridge containing the blood sample;a source of electromagnetic radiation;at least one photodetector;a processor for controlling the analyzer; andat least two calibration algorithms installed on the processor for measuring the at least two hemoglobin species; wherein the system is adjustable between a sealed configuration and an unsealed configuration; in the sealed configuration, and not in the unsealed configuration, the system comprises a closed air passage connecting the air bladder exit port to the blood storage conduit entrance for communicating the pressurized air from the air bladder exit port to the blood storage conduit entrance; and, in the unsealed configuration, and not in the sealed configuration, the blood storage conduit entrance is configured to receive the blood. |
