发明名称 PEPTIDES WITH NERVE-REGENERATING PROPERTIES
摘要 Use of the peptides of the general formula: A-B-L-Phe (or L-Ala)-D-Lys-L-Phe-Z-OH, where A represents one of the following groups: H-L-Met, H-L-Met(O), H-L-Met(O2), desamino-Met, desamino-Met(O) or desamino-Met(O2), B represents one of the following di-peptide fragments: Glu-His or Ala-Ala, where one amino acid residue of this di-peptide fragment can occur in the D form, and Z is either absent, or represents the amino acid residue Gly, or is the peptide fragment (10-16)-ACTH, where the amino acid L-Lys may be replaced, if desired, by D-Lys at position 11 of the (10-16)-ACTH fragment, and the functional derivatives thereof in promoting axonal regeneration.
申请公布号 WO8203388(A1) 申请公布日期 1982.10.14
申请号 WO1982EP00079 申请日期 1982.04.05
申请人 AKZO NV;GISPEN WILLEM HENDRIK 发明人 GISPEN WILLEM HENDRIK
分类号 A61K38/00;A61P25/00;A61P25/28;A61P25/30;C07K14/00;C07K14/695;(IPC1-7):07C103/52;61K37/40;61K37/02 主分类号 A61K38/00
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