| 摘要 |
Pyrrolidinones(I), useful for treatment of cerebral insufficiency and improve intellectual efficiency, were prepd. by cyclization of 4-(P-methoxybenzoylamino)butyric acid. For example, 20.0 g 4-(P-methoxybenzoylamino)butyric acid. was refluxed for 2 hr in a mixed soln. of 50 ml toluene and 9.2 ml thionyl chloride to give 1-(P-methoxybenzoyl)-2-pyrrolidinone(m.p. 119-120≦̸C).
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