发明名称 N2-ARYLSULFONYL-L-ARGININAMIDES AND THE PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF
摘要 N<2>-arylsulfonyl-L-argininamides of the general formula <CHEM> wherein R is <CHEM> wherein R1 is hydrogen or C1-C5 alkyl; and Ar is 1,2,3,4-tetrahydro- 8-quinolyl optionally substituted with at least one C1-C5 alkyl, or the acid addition salts thereof found useful as pharmaceutical agents, particularly as antithrombotics, pharmaceutical compositions containing these substances and processes for preparing these compounds are disclosed.
申请公布号 PH15662(A) 申请公布日期 1983.03.11
申请号 PH19530000229 申请日期 1979.08.24
申请人 MITSUBISHI CHEM IND 发明人 SHOSUKE OKAMOTO;AKIKO HITJIKATA;RYOJI KIKUMOTO;YOSHIKUNI TAMAO;KAZUO OHKUBO;SHINJI TONOMURA;TOHRU TEZUKA
分类号 A61K38/00;C07D401/12;C07K5/072 主分类号 A61K38/00
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