发明名称 7-[2-(2-AMINO-4-THIAZOLYL)-2-[(1-CARBOXY-1, 1-DIALKYL)ALKOXYIMINO]ACETAMIDO]CEPHEM SULFOXIDES
摘要 <p>7-¢2-(2-Amino-4-Thiazolyl)-2-¢(1-Carboxy-1,1-Dialkyl)Alkoxyimino!Acetamido!Cephem Sulfoxides Compounds of the formula wherein R is hydrogen, sodium, potassium, or certain ester groups; R1 is in the -configuration and is hydrogen or methoxy; R2 and R3 are independently selected from methyl, ethyl, i-propyl, and n-propyl; R4 is hydrogen, sodium, potassium or certain ester groups, and X is hydrogen, -O-?-lower alkyl, -O-?NH2, ,, ; R6 is hydrogen or lower alkyl; R7 is hydrogen, lower alkyl, -(CH2)n-?-OR8, -(CH2)n-?-OR8, or -(CH2)n-N-(lower alkyl)2; R8 is hydrogen, sodium or potassium, n is an integer from 1 to 4; are disclosed. These compounds are useful as antibacterial agents.</p>
申请公布号 CA1147323(A) 申请公布日期 1983.05.31
申请号 CA19800348408 申请日期 1980.03.25
申请人 SQUIBB (E. R.) & SONS, INC. 发明人 CIMARUSTI, CHRISTOPHER M.;KOSTER, WILLIAM H.;SYKES, RICHARD B.
分类号 A61K31/545;A61K31/546;A61P31/04;C07D209/48;C07D277/20;C07D501/20;C07D501/36;C07D501/46;C07D501/57;(IPC1-7):C07D501/20 主分类号 A61K31/545
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