摘要 |
<p>7-¢2-(2-Amino-4-Thiazolyl)-2-¢(1-Carboxy-1,1-Dialkyl)Alkoxyimino!Acetamido!Cephem Sulfoxides Compounds of the formula wherein R is hydrogen, sodium, potassium, or certain ester groups; R1 is in the -configuration and is hydrogen or methoxy; R2 and R3 are independently selected from methyl, ethyl, i-propyl, and n-propyl; R4 is hydrogen, sodium, potassium or certain ester groups, and X is hydrogen, -O-?-lower alkyl, -O-?NH2, ,, ; R6 is hydrogen or lower alkyl; R7 is hydrogen, lower alkyl, -(CH2)n-?-OR8, -(CH2)n-?-OR8, or -(CH2)n-N-(lower alkyl)2; R8 is hydrogen, sodium or potassium, n is an integer from 1 to 4; are disclosed. These compounds are useful as antibacterial agents.</p> |