| 摘要 |
PURPOSE:To obtain a gel which enables rapid and simple analysis of body fluids and elaborate separation of macromolecular components such as protein, by controlling the composition of org. solvents used along with a monomer in polymerization and the ester reaction ratio in a saponification or a transesterification reaction. CONSTITUTION:As monomers, a polymerizable compound having one or more vinyl carboxylate groups and a crosslinkable monomer having an isocyanurate ring are used. For example, a liquid mixture comprising 100g of vinyl acetate, 37.5g of triallyl isocyanurate, 110g of n-butyl acetate, 27.5g of iso-octane and 3.4g of 2, 2'-azobisisobutyronitrile and 800ml of water containing small amounts of polyvinyl alcohol and sodium phosphate dissolved therein are subjected to suspension polymerization under stirring and heating to obtain a granular copolymer. The transesterification reaction of the copolymer is performed in a solution consisting of 47g caustic soda and 2l methanol to obtain a gel. 5-50wt% of the total org. solvent is one hardly dissolving a vinyl carboxylate polymer and the reaction is controlled so as to convert 0.4-0.8 parts by mole of the ester group in the copolymer into a hydroxyl group. |
