| 摘要 |
PURPOSE:To prepare the titled composition having excellent oral absorbability and useful as a drug effective to improve the coronary function, by adding capric acid (a medium fatty acid) to a mixture of ubidecarenone and oleic acid (a higher fatty acid). CONSTITUTION:The objective ubidecarenone having improved oral absorbability, is obtained by adding ubidecarenone of formula to a mixture of oleic acid and capric acid. The weight ratio of oleic acid to capric acid is preferably 1:1, and the amount of ubidecarenone is 0.03-0.10pts.wt. per 1pt.wt. of the mixture. The composition can be prepared by mixing oleic acid with molten capric acid, and adding molten ubidecarenone to the mixture. The obtained mixture is filled in a soft capsule in the molten state, or is solidified and formed to the form suitable for oral administration. It may be used as granules, tablets, etc.
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