| 摘要 |
<p>G.1182 QUINOLONE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS Compounds of the following formula are described: (I) in which n is 0, 1 or 2, R1 is C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio, C1-4 alkylsulphonyl, trifluoromethyl, halo or nitro, and R2 and R3 are each independently hydrogen or C1-4 alkyl, and salts thereof. The compounds are useful in the treatment of immediate hypersensitivity conditions and are prepared by reaction of the appropriate formylquinolone with malonic acid, ylid or phosphonate.</p> |
