发明名称 |
TREATMENT OF NEUROBLASTOMA WITH HISTONE DEACETYLASE INHIBITORS |
摘要 |
Provided herein are combinations comprising an HDAC inhibitor and retinoic acid for the treatment of neuroblastoma in a subject in need thereof. Also provided herein are methods for treating neuroblastoma in a subject in need thereof, comprising administering to the subject an effective amount of the above HDAC inhibitor or combination, comprising administering to the subject in need thereof an effective amount of the above HDAC inhibitor or combination. Also provided herein is a method for predicting whether a neuroblastoma patient will respond to treatment with a combination comprising an HDAC inhibitor and retinoic acid. |
申请公布号 |
US2016339022(A1) |
申请公布日期 |
2016.11.24 |
申请号 |
US201615130351 |
申请日期 |
2016.04.15 |
申请人 |
Acetylon Pharmaceuticals Inc. |
发明人 |
Tamang David Lee;Jones Simon S.;Yang Min |
分类号 |
A61K31/505;A61K31/496;A61K31/5377 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Boston MA US |