| 发明名称 |
Liposomes Useful for Drug Delivery |
| 摘要 |
The present invention provides liposome compositions containing substituted ammonium and/or polyanion, and optionally with a desired therapeutic or imaging entity. The present invention also provide methods of making the liposome compositions provided by the present invention. |
| 申请公布号 |
US2016338956(A1) |
申请公布日期 |
2016.11.24 |
| 申请号 |
US201615227631 |
申请日期 |
2016.08.03 |
| 申请人 |
Merrimack Pharmaceuticals, Inc. |
发明人 |
Hong Keelung;Drummond Daryl C.;Kirpotin Dmitri |
| 分类号 |
A61K9/127;A61K47/26;A61K47/10;A61K31/4745;A61K47/24;A61K47/28 |
主分类号 |
A61K9/127 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pharmaceutical composition comprising irinotecan sucrose octasulfate precipitated in a matrix comprising one or more phospholipids, wherein the matrix has a size of approximately 110 nm and comprises a total of 500-550 mg irinotecan base per mmol of total phospholipids. |
| 地址 |
Cambridge MA US |
